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K008944PAnti-SLC22A17 Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008944PAnti-SLC22A17 Polyclonal Antibody
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- 简介
背景资料：Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
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