首页 >
产品展厅
> K008900PAnti-SPAG1 Polyclona...
K008900PAnti-SPAG1 Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008900PAnti-SPAG1 Polyclonal Antibody
查看相似产品 >
- 简介
背景资料：The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
...
联系我们
推荐产品
产品展厅
