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K008893PAnti-RASSF1 Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008893PAnti-RASSF1 Polyclonal Antibody
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- 简介
背景资料：This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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