首页 >
产品展厅
> K008818PAnti-DUSP8 Polyclona...
K008818PAnti-DUSP8 Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008818PAnti-DUSP8 Polyclonal Antibody
查看相似产品 >
- 简介
背景资料：The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.
...
联系我们
推荐产品
产品展厅
