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K008778PAnti-AD7C-NTP Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008778PAnti-AD7C-NTP Polyclonal Antibody
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- 简介
背景资料：The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.
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