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K008682PAnti-UBXN1 Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008682PAnti-UBXN1 Polyclonal Antibody
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- 简介
背景资料：Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
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