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K008677PAnti-DENND1B Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K008677PAnti-DENND1B Polyclonal Antibody
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- 简介
背景资料:Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.
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