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K009274PAnti-CFH Polyclonal Antibody
2020-03-04
产品详情
- 产地 北京
- 产品名称K009274PAnti-CFH Polyclonal Antibody
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- 简介
背景资料:This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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