首页 >
产品展厅
> 人基质金属蛋白酶抑制剂3 Elis...
人基质金属蛋白酶抑制剂3 Elisa试剂盒
2020-08-10
产品详情
- 产地 北京
- 产品名称人基质金属蛋白酶抑制剂3 Elisa试剂盒
查看相似产品 >
- 简介
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14
...
联系我们
推荐产品