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大鼠趋化因子(fractalkine/CX3CL1) Elisa试剂盒
2020-08-10
产品详情
- 产地 北京
- 价格:询价
- 产品名称大鼠趋化因子(fractalkine/CX3CL1) Elisa试剂盒
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- 简介
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.
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