首页 >
产品展厅
> Anti-SPIN2B Polyclonal Antib...
Anti-SPIN2B Polyclonal Antibody
2020-08-10
产品详情
- 产地 北京
- 产品名称Anti-SPIN2B Polyclonal Antibody
查看相似产品 >
- 简介
Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.
...
联系我们
推荐产品
产品展厅
