- 产品名称:人吲哚胺2,3-二加氧酶 Elisa试剂盒
- 品牌:Solarbio
- 产地:北京
- 样本:血清/血浆/细胞培养上清
- 应用:Elisa试剂盒
- 检测方法:双抗体夹心法
- 检测限:125-8000 pg/Ml
- 数量:999
- 货号:SEKH-0502
- 用途范围:Human
- 是否进口:否
- 保存条件:-20
- 适应物种:Human
- 单 价:2600 元/盒
- 最小订货量:1盒
- 供货能力:999
详细描述:
Indoleamine 2,3-dioxygenase (IDO) is a heme-containing intracellular dioxygenase catalyzing the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine. IDO is widely expressed in dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. In immune cells, its expression is mainly induced by cytokines such as IFN gamma, IFN alpha, IFN beta, and IL-10. IDO has an antimicrobial function and induces immunosuppression during infection, pregnancy, transplantation, autoimmunity, and neoplasia.